Use of Plants as Bioreactors for Peptide Production
(Collaborative project with UM and MARDI)
Production of antibody in transgenic plants for viral resistance and use in plant pathogen diagnostics.
Plants and plant cells are natural bioreactors, performing some of natures' most complex biochemistry and producing a wide range of biochemical products. Current technology allows the modification of plants to produce specific products, including proteins and peptides with commercial value, such as antibodies ("plantibodies"), hormones, enzymes, antibiotics and vaccines. We are exploring the possibility of using local crop plants for the production of value added products with relevance to local industry and for the development of diagnostic kits. In this study we have focused on the synthesis and modeling of a soluble tag-fusion single chain variable fragment (ScFv) antibody to cucumber mosaic virus (CVM) coat protein in tobacco plants.
|
| Variable Heavy Chain of ScFv "plantibody" |
Principal Investigators at MUST
 Back
|
