Isolation and Characterization of Bacteria Capable of Bioleaching of Metal Ores
A variety of microorganisms are capable of growing and acquiring their energy for growth from the oxidation-reduction of reduced sulfur compounds, sulfur and metals (commonly iron). Harnessing this natural process that serves as a means of bioleaching for commercial purposes has opened up many opportunities to a growing industry of biomining. We are interested in isolating and classifying new strains of bacteria that are related to bioleaching of metal ores, especially the acidophilic, chemolithotrophic bacteria Acidithiobacillus spp. (previously known as Thiobacillus spp.). The role of acidophilic bacteria in leaching metal depends upon their ability to oxidize ferrous iron, and metal sulfide. Our physiological studies include nutritional questions, isolation and characterization of enzymes to elucidate the functions and pathways of enzymes that are useful for bioleaching.
We are also interested in understanding the molecular determinants of the structure and function of enzymes that catalyzes the bioleaching reactions, as well as incorporating interdisciplinary studies in inorganic chemistry, biochemistry, bioinformatics, molecular biology and microbiology. Recent advancements and progress in the genetic manipulation and engineering of microorganisms for commercial purposes promise to create ways for perfecting ore-processing, enhance productivity and facilitate the recovery of metals in mining industries. In addition, this course of research could also yield methods for the microbial treatment of metal-contaminated waste water, the recycling of metals and the reclamation of land (bioremediation).
Principal Investigators at MUST
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